"Jim Shepard is a fiction writer of peculiar but tantalizing gifts." The New York Times

In a tiny settlement on the west coast of Greenland, 11-year-old Aleq and his best friend, frequent trespassers at a mining site exposed to mountains of long-buried and thawing permafrost, carry what they pick up back into their village, and from there Shepard's harrowing and deeply moving story follows Aleq, one of the few survivors of the initial outbreak, through his identification and radical isolation as the likely index patient. While he shoulders both a crushing guilt for what he may have done and the hopes of a world looking for answers, we also meet two Epidemic Intelligence Service investigators dispatched from the CDC--Jeannine, an epidemiologist and daughter of Algerian immigrants, and Danice, an MD and lab wonk. As they attempt to head off the cataclysm, Jeannine--moving from the Greenland hospital overwhelmed with the first patients to a Level 4 high-security facility in the Rocky Mountains--does what she can to sustain Aleq.

Both a chamber piece of multiple intimate perspectives and a more omniscient glimpse into the megastructures (political, cultural, and biological) that inform such a disaster, the novel reminds us of the crucial bonds that form in the midst of catastrophe, as a child and several hyper-educated adults learn what it means to provide adequate support for those they love. In the process, they celebrate the precious worlds they might lose, and help to shape others that may survive.

"Jim Shepard is a fiction writer of peculiar but tantalizing gifts." - The New York Times

"Paced like a prophetic thriller . . . Shepard has frequently employed research as a foundation for his literary creations, but never before in such pulse-racing fashion . . . Readers will find themselves in territory that feels eerily familiar-panic, politics, uncertainty, fear, a resistance to quarantine, an overload of media noise-as Shepard's command of tone never lets the tension ease . . . All the narrative propulsion of escapist fiction without the escape." - Kirkus Reviews (starred review)

"Phase Six is a fast-paced, suspenseful story about what happens when a different microbe is unleashed on the world . . . [A]n ode to family, friends, lovers, hard work and the beautiful, heartbreaking innocence of childhood" - Daily Mail

"Thrilling . . . a very human story, full of emotion and inevitable sorrow and pain." - Irish Indepedent