This publication explores essential concepts related to entrepreneurship, innovation, and technology commercialization. It provides insight into the fundamental ideas, models, practices, and strategies of technology-intensive entrepreneurial ventures. Drawing on the academic and professional experience of the authors, this book is grounded in theory yet managerially practical. The range of topics explored in this book have been empirically validated by research and endorsed in management practice. It is unlike most innovation and technology commercialization books, as it takes a managerial, as opposed to a scientific, perspective. In doing so, it uniquely prepares individuals with entrepreneurial and management capabilities for the innovation-focused and technology-centric business environment of the future.