This issue of Emergency Medicine Clinics on Seizures will focus on topics such as: Seizure in the Emergency Department: Epidemiology and Cost to Society;Seizure and Status Epilepticus: Pathophysiology and Definitions ;The Diagnosis and Management of Seizures and Status Epilepticus in the Pre-hospital Setting ;The Emergency Department Evaluation of the Patients Who Present with a First Time Seizure;Generalized Convulsive Status Epilepticus: Treatment Guidelines and Protocols;Nonconvulsive Status Epilepticus;Antiepileptic Drugs: The Old and the New;Seizures in Pregnancy / Eclampsia and Psychogenic Seizures