Peripheral vascular disease (PVD) affects more than 30 million people worldwide, most often individuals over age 65. Despite this, PVD remains a disease with which many clinicians are unfamiliar. Peripheral Vascular Disease helps medical professionals of different backgrounds and training apply resources adequately to benefit individual patients. The authors provide a description of relevant vascular anatomy and pathophysiology, a focused review of diagnostic modalities used in screening for PVD, and contemporary medical and interventional treatments used for PVD. Generous use of bullet points, condensed tables, high-quality figures, and diagrams facilitate easy comprehension of a multifaceted and serious condition.