The most engaging and accessible account of cancer biology which clearly links our understanding of cancer with the development of new therapeutics. Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics offers an accessible, engaging, and optimistic account of cancer biology for undergraduate and graduate students. Key features - Describes the theoretical basis of cancer biology and shows how this theory is applied to develop new cancer therapies, giving students a clear appreciation of how theoretical knowledge can be translated into therapeutic strategies - Draws on the latest research in cancer biology - Features a variety of learning features to help students engage with the concepts presented: 'Pause and think'; 'How do we know that?'; 'In the clinic'; self-tests; and activities New to this edition - New themes that weave throughout the book, such as the two-way interactions between the microenvironment and the tumour, systemic effects of cancer, and the role of plasticity and heterogeneity in cancer evolution - Expanded coverage of cancer genomics, including single cell genomics and spatial transcriptomics, highlighted in the concluding chapter - A new feature called 'In the clinic' that highlights current or potential applications of cancer biology to clinical practice - Updates on newly approved cancer therapeutics - Includes additional primary data from the literature and key references to provide a resource of up-to-date experimental evidence - Expanded artwork programme and new 'figure sequences' (in the enhanced e-book) to help readers understand molecular pathways over time Digital formats and resources The 6th edition is available for students and institutions to purchase in a variety of formats: the e-book and Science Trove offer a mobile experience and convenient access along with multiple choice questions, audio clips, functionality tools, navigation features and links that offer extra learning support. For more information about e-books, please visit https://www.oxfordtextbooks.co.uk/ebooks

"A comprehensive resource outlining the principles of cancer biology, with a clear structure and good use of diagrams and learning features." - Alison Simons, Senior Lecturer, Birmingham City University, UK

"An excellent overview of cancer biology with broad coverage and clear prose and figures." - William Thierfelder, Associate Professor of Biology, Union University, USA

"This textbook has extensive learning features that help to improve the reader's user experience and knowledge of scientific concepts. It is extremely well detailed and concise with a clear structure throughout. Specialised when needed, simplified whenever possible, highly recommend." - Daniel O'Neill, Student, Aberystwyth University

"This textbook is a clear and comprehensive overview of molecular biology in the context of cancer research and treatment. It is accessible to undergraduates and a helpful refresher for postgraduates as well." - Holly English, Student, University College Dublin

"I loved this book! It is stimulating and makes some very challenging work readable and accessible. The various learning features are useful and supportive, and serve to encourage a [strong] level of engagement." - Gary Edward Spencer, Student, Canterbury Christ Church University

"Overall I feel that the way in which the book explains complex mechanisms is outstanding. Where other textbooks can often leave you feeling perplexed, this textbook simplifies everything into manageable chunks." - Rebecca Kemp, Student, University of Nottingham