This book suggests a radical departure in approaching the mind-body problem. Instead of trying to causally relate subjective experience to the functioning of the body, it begins with the notion of the psychosomatic unity of the individual and looks for its conditions of possibility. This text shows that what makes this unity possible is the generalized entanglement relation that connects a person's subjective experience with its body functioning in a specific way.In addition to providing a significant contribution to the long-standing philosophical debate about the nature of the mind-body connection, this change of perspective based on the concept of generalized entanglement allows for exploring a holistic approach to health. It can for example explain the existence of body memory and leads to a better understanding of the genesis and evolution of internal diseases, allowing for the development of mind-body therapies. This volume also provides new insights into mental disorders and sets the theoretical basis of self-healing methods appealing to students, researchers and professionals in the fields.