William Burroughs as author and pioneer continues to attract large readership Lifts the lid on the pharmacological industry and its limitations Strong public interest in neuroscience

Lees draws on Burroughs' search for an addiction cure to discover a ground-breaking treatment for shaking palsy, and learns how to use the deductive reasoning of Sherlock Holmes to diagnose patients. Lees follows Burroughs into the rainforest and under the influence of yage (ayahuasca) gains insights that encourage him to pursue new lines of pharmacological research and explore new forms of science.