This issue of Veterinary Clinics of North America: Food Animal Practice focuses on Disaster Response and Beef Cattle Operations, with topics including: Flooding; Tornadoes; Blizzard and range cattle; Blizzard and confined cattle; Wildfire and range cattle; Heat stress episodes in confined cattle; Foreign animal disease outbreaks; Truck accidents on highways; Cattle assessment on site during emergencies; Humane euthanasia and carcass disposal; Emergency nutrition for cattle; Communication during natural disasters and working with authorities; and Mental health during times of disaster.