This publication presents the outcomes of an IAEA coordinated research project on assessing the national economic effects of nuclear programmes in participating Member States. It provides a short description of the extended input–output model for sustainable power generation (EMPOWER), developed by the IAEA, and presents concise summaries of its applications. It further includes the results produced by the contributing research teams and summarizes general insights drawn from the national studies. The publication illustrates the state of the art of assessing macroeconomic impacts of nuclear energy programmes. It is expected to support further applications of advanced models to improve the understanding of macroeconomic and sectoral impacts of building and operating nuclear power plants