"All About My Mother" is a passionate hymn to the strength and spirit of women; a kaleidoscopic drama embracing motherhood, love and desire; and, a homage to the great Hollywood movies. Following the tragic death of her beloved son, Manuela goes to Barcelona in search of the father. But before she can exorcise her guilt she gets caught up in the lives of three women: Agrado, a long-lost transexual friend; Rosa, a young nun in search of love; and, Huma Rojo, the famous actress Manuela's son so admired. As Manuela's life regains meaning, her son's father returns and her journey of discovery draws to a redemptive close.