Present-day Minneapolis. Dr Ana Jovanovic, oncologist, goes against the advice of her hospital's tumour board and schedules her patient Jonathan for exploratory surgery. She is proved right when the surgery reveals that he has cancer. But when tragedy strikes, Ana is sent into a tailspin. She takes an unplanned sabbatical, hoping to rediscover herself outside her dual, devouring roles of doctor and mother to fifteen-year-old Maggie. Now sharply aware of her own mortality, the doctor is confronted with decisions about quality of life and quality of death.