Steve Rogers knows the art of survival better than most. Decades under ice will do that to a man. But the Avengers chipped more than rock-hard morality and super-strength out from under that permafrost. When Cap takes out a terrorist cell threatening to poison the world, he'll discover a threat far more deadly. An incurable virus has hidden in his body for years-and now it's come to the surface. To save the world, he'll have to return to his own personal hell: deep freeze.

And he'll have to take an old friend with him. Having survived his own death by inhabiting a clone of Steve Rogers, the Red Skull has inherited the virus-and he's a little less willing to play martyr. As the deadly disease shifts and evolves, new patterns emerge. Can Captain America contain the Red Skull before the virus runs rampant?