Cooperative Control of Multi-Agent Systems with Uncertainties proposes a hierarchical design framework that places uncertainties related to system models in the decentralized control layer (bottom layer) and the ones related to the communication (as well as physical interaction) between the agents in the distributed decision-making layer (top layer). The book shows that the two layers meet separation principles under certain conditions so that through the two-layer design framework any challenges can be resolved independently and so that design complexities will not increase with the level of uncertainties. In addition, in order to solve the problem of energy limitation of agents, the book also studies the event-driven cooperative control of multi-agent systems, which can effectively reduce energy consumption of agents and increase their operational lifespan.