This text explains the key biochemical and cell biological principles behind some of today's most commonly used applications of molecular genetics, using clear terms and well-illustrated flow schemes. The book is divided into several sections and moves from basic to advanced topics while providing a concise overview of fundamental concepts in modern biotechnology. Each chapter concludes with a Laboratory Practicum describing a hypothetical research objective and the sequence of steps that are most often used to investigate biological questions using molecular genetic methods. In addition, the book provides informative summaries of the latest advances in molecular genetics, using attractive illustrations and a comprehensive reference list.

This text also introduces the use of Internet resources through the World Wide Web as a powerful new tool in molecular genetic research. Seven appendices are included in the book, providing a convenient information resource for properties of nucleic acids, protein and restriction enzymes, a description of common E. coli genetic markers and gel electrophoresis parameters, as well as a list of useful Internet address sites.Ein handlicher, leicht verstandlich geschriebener Leitfaden uber die wissenschaftlichen Grundlagen der gebrauchlichsten Anwendungen der Molekulargenetik in der biologischen und biomedizinischen Forschung. Dieses Buch schafft die Verbindung zwischen veroffentlichten Protokollen und Berichten zu Versuchsergebnissen, indem es erlautert, wie verschiedene molekulare Techniken kombiniert werden, um positive Forschungsergebnisse zu erzielen. Es ist fur Studenten und Forscher gleicherma?en geeignet. Die funf wichtigsten Gebiete der angewandten Molekulargenetik werden ausfuhrlich diskutiert. Themenschwerpunkt und Stofforganisation machen dieses Werk zu einer echten Alternative: Es ist handlich, uberschaubar und topaktuell. (yTIS;7/99)