This issue of the Psychiatric Clinics, edited by Dr. Rajnish Mago, will cover a variety of side effects of Psychopharmacotherapy. The topics discussed include principles of evaluation and management; sexual dysfunction; adverse effects on pregnancy due to bipolar medications; metabolic adverse effects of antipsychotics; adverse effects of psychotropic medications on sleep; antidepressants and suicide; and adverse effects of electroconvulsive therapies, among others.