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The tranquillity of a quiet town is shattered by brutal murders. A methodical, intelligent and manipulative serial killer with a penchant for medical experimentation has long evaded the police, hiding in the shadows of the Louisiana bayou. He has been working hard to complete his most heinous crime, taunting the authorities as they desperately try to catch up with him.

Today he is back on the prowl. Who will be his victim?"

At the same time, forensic scientist Ren Mueller, who has an impressive knowledge of historical crimes and years of experience working in a forensic science office, is on the hunt. Although the doctor's desk is overflowing with criminal cases, she becomes interested in the killer, who is becoming increasingly brazen. Ren begins to piece together the puzzle between the victims and decides that she is the best candidate to track down the killer...