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The publication is prepared in accordance with the educational and professional programme for bachelor's degree in 0305 «Economics and Entrepreneurship», taking into account the requirements of the Bologna Declaration. The textbook presents a course of lectures on the discipline "Regional Economics" in a structural and logical form, contains questions for self-control, topics for essays and test tasks for each topic, appendices, and a bibliography. Designed for students of higher education institutions of III-IV accreditation levels. It can be used by postgraduate students, specialists of enterprises and organisations interested in deepening their knowledge of regional economic development.