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Sincere, sarcastic and unapologetically profane, Preacher charts the epic journey of Reverend Jesse Custer as he tracks down a fugitive God to hold Him accountable for the suffering of His creation.

In search of divine revelation, Jesse and his friends make a righteous path through a fallen world and the very soul of America, from the mansions of San Francisco to the foothills of the Alps and the sawdust-strewn bars of New York City, facing all the evil that Earth and Heaven can unite.