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One day, a small town in Maine is suddenly cut off from the outside world by a transparent dome. No one can get in, no one can get out. And as panic spreads through the town, local businessman Big Jim takes over.

A new police force and the gangster style of the new chief lead to an increase in arbitrariness and violence under the Dome. The dark secrets of the residents come to light, while the death toll rises. And only a small group of people, together with former army officer Dale "Barbie" Barbara, are trying to find out the reasons for the Dome's appearance and get rid of it. All of them risk their lives, because Big Jim is not going to give up his newfound, almost unlimited power.