This publication provides States and operators with advice on defining, implementing, maintaining or enhancing their nuclear security regime for the protection of uranium ore concentrate against unauthorized removal. It defines prudent management practice as required by IAEA Nuclear Security Series No. 13, Nuclear Security Recommendations on Physical Protection of Nuclear Material and Nuclear Facilities (INFCIRC/225/Revision 5), for this category of material. This advice can be adopted in the form of regulations or applied as voluntary standards. States, regulatory bodies, and industry may choose to tailor their implementation of this advice to meet their national circumstances.