This book highlights recent developments of organic and inorganic nanomedicine that play a major role in anti-angiogenic cancer therapy.  In addition, the authors present examples of nanomedicine based anti-angiogenic agents and their applications in cancer therapy.  Angiogenesis is a pathophysiological phenomenon that modulates cell proliferation and cell migration and plays important roles in cancer.  Anti-angiogenic nanotherapies have gained immense attention in recent times as alternative cost-effective therapies that opened a new dimension in cancer theranostics.  Further the challenges of the anti-angiogenic nanotherapies and possible future perspective are detailed.