This book focuses on fault diagnosis for linear discrete time-varying (LDTV) systems and its applications in modern engineering processes, with more weighting placed on the development of theory and methodologies. A comprehensive and systematic study on fault diagnosis for LDTV systems is provided, covering H∞-optimization-based fault diagnosis, H∞-filtering-based fault diagnosis, parity space-based fault diagnosis, Krein space technique-aided fault detection and fault estimation, and their typical applications in linear/nonlinear processes such as satellite attitude control systems and INS/GPS systems. This book benefits researchers, engineers, and graduate students in the fields of control engineering, electrical and electronic engineering, instrumentation science, and optoelectronic engineering.