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Caliban's War is the second novel in the Expansion series by American science fiction writers Daniel Abraham and Ty Frank, who have dropped the pseudonym James S. A. Corey. In terms of genre, this work, as well as the entire series, is a rather harmonious combination of hard science fiction, space opera, horror, political detective and action movie.

A year has passed since the Eros "incident", when an asteroid was absorbed by a hostile protomolecule capable of changing the structure of all living organisms. This infection threatened the entire solar system, but the now-distorted Eros was directed to Venus. There, under the thick layer of the atmosphere, the protomolecule grows and waits."

Meanwhile, the monster infected by it suddenly appears on Ganymede, the breadbasket of all the outer planets. However, its attack is enough to rekindle the extinct conflict between Mars and Earth. As a result, Ganymede is nearly destroyed, the system's precarious stability is threatened, and the protomolecule seems to be making a comeback.

We follow the salvation of humanity from behind the shoulder of the same idealistic Captain Jim Golden; Krisjen Awasarala, the only one in the UN Office who hasn't lost her sanity; renegade sergeant Bobbi Draper of the Martian Space Marines; and scientist Prax Meng, who is simply looking for his daughter, who was lost during the conflict.