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The textbook is devoted to teaching the sections of the discipline "Databases in Information Systems", which provides educational material on the design and use of information systems based on relational database management systems. The textbook addresses the theoretical foundations of designing relational databases and information systems that use relational databases, the composition and structure of the structured query language for relational databases - SQL, and provides material on the practical creation and further use of relational databases based on well-known SQL servers. The authors provide information on the development of application programmes with access to databases in the C# programming language.