The second volume of this introduction into analysis deals with the integration theory of functions of one variable, the multidimensional differential calculus and the theory of curves and line integrals. The modern and clear development that started in Volume I is continued. In this way a sustainable basis is created which allows the reader to deal with interesting applications that sometimes go beyond material represented in traditional textbooks. This applies, for instance, to the exploration of Nemytskii operators which enable a transparent introduction into the calculus of variations and the derivation of the Euler-Lagrange equations.