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Given an amazing sense of smell and a phenomenal memory, Agatha Mystery dreams of becoming a writer, but that's in the future. For now, she is a great detective! Together with her simple-minded cousin Larry, a student at a detective school, she travels the world solving the most intricate mysteries. They are assisted by a loyal major, a naughty Siberian cat, and a host of strange relatives.

Theft in the Vatican

The newly discovered will of Raphael, the famous Italian artist of the 16th century, has been stolen from the Vatican's Secret Archives. Agatha and Larry Mystery immediately set off for Italy. Fortunately, their uncle Algernon, a paleographer, lives in Rome. Together they will have to find the missing letter and make a sensational discovery...