This issue of Pediatric Clinics offers an update on Advances in Neonatology. Guest Editors Drs. Lucky Jain and David Carlton have assembled a panel of world-class experts who offer reviews on topics including Trends in birthing, gestational age, birth weight and mortality in newborns; Late Prematurity; Advances in newborn resuscitation; Approaches to infants with congenital anomalies; Advances in neonatal surgery; Respiratory failure in the term and near term infant; Mechanical ventilation of the newborn; Pulmonary hypertension in the newborn; Bronchopulmonary dysplasia; Extracorporeal membrane oxygenation; Necrotising enterocolitis; Hyperbilirubinemia; Retinopathy of Prematurity; Surgical approaches to an infant with congenital heart disease; Hypoxic ischemic encephalopathy; Neonatal sepsis; and Quality improvement in neonatology.